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Comparison between single-marker analysis using Merlin and multi-marker analysis using LASSO for Framingham simulated data

We compared family-based single-marker association analysis using Merlin and multi-marker analysis using LASSO (least absolute shrinkage and selection operator) for the low-density lipoprotein phenotype at the first visit for all 200 replicates of the Genetic Analysis Workshop 16 Framingham simulate...

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Detalhes bibliográficos
Main Authors: Sung, Yun Ju, Rice, Treva K, Shi, Gang, Gu, C Charles, Rao, DC
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795924/
https://ncbi.nlm.nih.gov/pubmed/20018017
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