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A variance component-based gene burden test
We propose a novel variance component approach for the analysis of next-generation sequencing data. Our method is based on the detection of the proportion of the trait phenotypic variance that can be explained by the introduction of a new variance component that accounts for the local gene-specific...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4143638/ https://ncbi.nlm.nih.gov/pubmed/25519388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S1-S49 |
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