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A Kernel of Truth: Statistical Advances in Polygenic Variance Component Models for Complex Human Pedigrees

Statistical genetic analysis of quantitative traits in large pedigrees is a formidable computational task due to the necessity of taking the non-independence among relatives into account. With the growing awareness that rare sequence variants may be important in human quantitative variation, heritab...

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Detalhes bibliográficos
Main Authors: Blangero, John, Diego, Vincent P., Dyer, Thomas D., Almeida, Marcio, Peralta, Juan, Kent, Jack W., Williams, Jeff T., Almasy, Laura, Göring, Harald H. H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019427/
https://ncbi.nlm.nih.gov/pubmed/23419715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-407677-8.00001-4
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