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Application of noncollapsing methods to the gene-based association test: a comparison study using Genetic Analysis Workshop 18 data
Rare variants have been proposed to play a significant role in the onset and development of common diseases. However, traditional analysis methods have difficulties in detecting association signals for rare causal variants because of a lack of statistical power. We propose a two-stage, gene-based me...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4143635/ https://ncbi.nlm.nih.gov/pubmed/25519333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S1-S53 |
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