Alternative splicing in osteoclasts and Paget’s disease of bone

BACKGROUND: Mutations in the SQSTM1/p62 gene have been reported in Paget’s disease of bone (PDB), but they are not sufficient to induce the pagetic osteoclast (OC) phenotype. We hypothesized that specific RNA isoforms of OC-related genes may contribute to the overactivity of pagetic OCs, along with...

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Main Authors: Klinck, Roscoe, Laberge, Gino, Bisson, Martine, McManus, Stephen, Michou, Laëtitia, Brown, Jacques P, Roux, Sophie
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143580/
https://ncbi.nlm.nih.gov/pubmed/25115182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-014-0098-1
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