Alternative splicing in osteoclasts and Paget’s disease of bone

BACKGROUND: Mutations in the SQSTM1/p62 gene have been reported in Paget’s disease of bone (PDB), but they are not sufficient to induce the pagetic osteoclast (OC) phenotype. We hypothesized that specific RNA isoforms of OC-related genes may contribute to the overactivity of pagetic OCs, along with...

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Bibliografiska uppgifter
Huvudupphovsmän: Klinck, Roscoe, Laberge, Gino, Bisson, Martine, McManus, Stephen, Michou, Laëtitia, Brown, Jacques P, Roux, Sophie
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143580/
https://ncbi.nlm.nih.gov/pubmed/25115182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-014-0098-1
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