Beta-cell-specific production of IL6 in conjunction with a mainly intracellular but not mainly surface viral protein causes diabetes

Inflammatory mechanisms play a key role in the pathogenesis of type 1 and type 2 diabetes. IL6, a pleiotropic cytokine with impact on immune and non-immune cell types, has been proposed to be involved in the events causing both forms of diabetes and to play a key role in experimental insulin-depende...

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Autors principals: Van Belle, Tom L., Pagni, Philippe P., Liao, Jeanette, Sachithanantham, Sowbarnika, Dave, Amy, Hani, Amira Bel, Manenkova, Yulia, Amirian, Natalie, Yang, Cheng, Morin, Bret, Zhang, Haiqing, Campbell, Iain L., von Herrath, Matthias G.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143487/
https://ncbi.nlm.nih.gov/pubmed/24582317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2014.02.002
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