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Unexpected Phenotype of Mice Lacking Shcbp1, a Protein Induced during T Cell Proliferation

T cell development and activation are highly regulated processes, and their proper execution is important for a competent immune system. Shc SH2-domain binding protein-1 (Shcbp1) is an evolutionarily conserved protein that binds to the adaptor protein ShcA. Studies in Drosophila and in cell lines ha...

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Bibliografiske detaljer
Main Authors: Buckley, Monica W., Arandjelovic, Sanja, Trampont, Paul C., Kim, Taeg S., Braciale, Thomas J., Ravichandran, Kodi S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143286/
https://ncbi.nlm.nih.gov/pubmed/25153088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105576
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