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NRPquest: Coupling Mass Spectrometry and Genome Mining for Nonribosomal Peptide Discovery

[Image: see text] Nonribosomal peptides (NRPs) such as vancomycin and daptomycin are among the most effective antibiotics. While NRPs are biomedically important, the computational techniques for sequencing these peptides are still in their infancy. The recent emergence of mass spectrometry technique...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mohimani, Hosein, Liu, Wei-Ting, Kersten, Roland D., Moore, Bradley S., Dorrestein, Pieter C., Pevzner, Pavel A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society and American Society of Pharmacognosy 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143176/
https://ncbi.nlm.nih.gov/pubmed/25116163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np500370c
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