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Imaging mass spectrometry and genome mining via short sequence tagging identified the anti-infective agent arylomycin in Streptomyces roseosporus

Here, we described the discovery of anti-infective agent arylomycin and its biosynthetic gene cluster in an industrial daptomycin producing strain Streptomyces roseosporus. This was accomplished via the use of MALDI imaging mass spectrometry (IMS) along with peptidogenomic approach in which we have...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Liu, Wei-Ting, Kersten, Roland D., Yang, Yu-Liang, Moore, Bradley S., Dorrestein, Pieter C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251218/
https://ncbi.nlm.nih.gov/pubmed/21999343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2040877
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