Development of multinuclear polymeric nanoparticles as robust protein nanocarriers

One limitation of current biodegradable polymeric nanoparticles is their inability to effectively encapsulate and sustainably release proteins while maintaining protein bioactivity. Here we report the engineering of a PLGA-polycation nanoparticle platform with core-shell structure as a robust vector...

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Main Authors: Wu, Jun, Kamaly, Nazila, Shi, Jinjun, Zhao, Lili, Xiao, Zeyu, Hollett, Geoffrey, John, Rohit, Ray, Shaunak, Xu, Xiaoyang, Zhang, Xueqing, Kantoff, Philip W., Farokhzad, Omid C.
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143165/
https://ncbi.nlm.nih.gov/pubmed/24990548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201404766
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