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Polymeric Nanoparticles Amenable to Simultaneous Installation of Exterior Targeting and Interior Therapeutic Proteins

Effective delivery of therapeutic proteins a formidable challenge. Herein, using a unique polymer family with a wide-ranging set of cationic and hydrophobic features, we developed a novel nanoparticle (NP) platform capable of installing protein ligands on the particle surface and simultaneously carr...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Zhu, Xi, Wu, Jun, Shan, Wei, Tao, Wei, Zhao, Lili, Lim, Jong-Min, D’Ortenzio, Mathew, Karnik, Rohit, Huang, Yuan, Shi, Jinjun, Farokhzad, Omid C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835185/
https://ncbi.nlm.nih.gov/pubmed/26846161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201509183
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