Development of multinuclear polymeric nanoparticles as robust protein nanocarriers

One limitation of current biodegradable polymeric nanoparticles is their inability to effectively encapsulate and sustainably release proteins while maintaining protein bioactivity. Here we report the engineering of a PLGA-polycation nanoparticle platform with core-shell structure as a robust vector...

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Detalhes bibliográficos
Main Authors: Wu, Jun, Kamaly, Nazila, Shi, Jinjun, Zhao, Lili, Xiao, Zeyu, Hollett, Geoffrey, John, Rohit, Ray, Shaunak, Xu, Xiaoyang, Zhang, Xueqing, Kantoff, Philip W., Farokhzad, Omid C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143165/
https://ncbi.nlm.nih.gov/pubmed/24990548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201404766
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