Učitavanje...
Dimerization of HIV-1 protease occurs through two steps relating to the mechanism of protease dimerization inhibition by darunavir
Dimerization of HIV-1 protease (PR) subunits is an essential process for PR’s acquisition of proteolytic activity, which plays a critical role in the maturation of HIV-1. Recombinant wild-type PR (PR(WT)) proved to dimerize, as examined with electrospray ionization mass spectrometry; however, two ac...
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Glavni autori: | , , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
National Academy of Sciences
2014
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4142999/ https://ncbi.nlm.nih.gov/pubmed/25092296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1400027111 |
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