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Orthogonal dual thiol–chloroacetyl and thiol–ene couplings for the sequential one-pot assembly of heteroglycoclusters

We describe the first one-pot orthogonal strategy to prepare well-defined cyclopeptide-based heteroglycoclusters (hGCs) from glycosyl thiols. Both thiol–chloroactetyl coupling (TCC) and thiol–ene coupling (TEC) have been used to decorate cyclopeptides regioselectively with diverse combination of sug...

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Detalhes bibliográficos
Main Authors: Fiore, Michele, Daskhan, Gour Chand, Thomas, Baptiste, Renaudet, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142873/
https://ncbi.nlm.nih.gov/pubmed/25161711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.10.160
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