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TargetingTumor MetabolismWith 2-Deoxyglucose in Patients With Castrate-Resistant Prostate Cancer and Advanced Malignancies

BACKGROUND: A profound difference between cancer and normal tissues is the preferential utilization of glycolysis by cancer cells. To translate this paradigm in the clinic, we completed a phase I study of 2-deoxyglucose (2DG), and assessed 2DG uptake with fluorodeoxyglucose (FDG) positron emission t...

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Detalhes bibliográficos
Main Authors: Stein, Mark, Lin, Hongxia, Jeyamohan, Chandrika, Dvorzhinski, Dmitri, Gounder, Murugesan, Bray, Kevin, Eddy, Simantini, Goodin, Susan, White, Eileen, DiPaola, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142700/
https://ncbi.nlm.nih.gov/pubmed/20687211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.21172
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