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A validated bioanalytical HPLC method for pharmacokinetic evaluation of 2-deoxyglucose in human plasma

2-deoxyglucose (2-DG), an analog of glucose, is widely used to interfere with the glycolysis in tumor cells and studied as a therapeutic approach in clinical trials. To evaluate the pharmacokinetics of 2-DG, we describe the development and validation of a sensitive HPLC fluorescent method for the qu...

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Detalhes bibliográficos
Publicado no:Biomed Chromatogr
Main Authors: Gounder, Murugesan K., Lin, Hongxia, Stein, Mark, Goodin, Susan, Bertino, Joseph R., Kong, Ah-Ng Tony, DiPaola, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522920/
https://ncbi.nlm.nih.gov/pubmed/21932382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bmc.1710
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