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Investigating the role of uncoupling of troponin I phosphorylation from changes in myofibrillar Ca(2+)-sensitivity in the pathogenesis of cardiomyopathy

Contraction in the mammalian heart is controlled by the intracellular Ca(2+) concentration as it is in all striated muscle, but the heart has an additional signaling system that comes into play to increase heart rate and cardiac output during exercise or stress. β-adrenergic stimulation of heart mus...

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Hlavní autoři: Messer, Andrew E., Marston, Steven B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142463/
https://ncbi.nlm.nih.gov/pubmed/25202278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00315
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