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Mitochondrial dynamics controlled by mitofusins regulate Agrp neuronal activity and diet-induced obesity

Mitochondria are key organelles in the maintenance of cellular energy metabolism and integrity. Here we show that mitochondria number decrease but their size increase in orexigenic Agrp neurons during the transition from fasted to fed to over-fed state. These fusion-like dynamic changes were cell-ty...

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Detalhes bibliográficos
Main Authors: Dietrich, Marcelo O., Liu, Zhong-Wu, Horvath, Tamas L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142434/
https://ncbi.nlm.nih.gov/pubmed/24074868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.09.004
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