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Mitochondrial dynamics controlled by mitofusins regulate Agrp neuronal activity and diet-induced obesity

Mitochondria are key organelles in the maintenance of cellular energy metabolism and integrity. Here we show that mitochondria number decrease but their size increase in orexigenic Agrp neurons during the transition from fasted to fed to over-fed state. These fusion-like dynamic changes were cell-ty...

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Hlavní autoři: Dietrich, Marcelo O., Liu, Zhong-Wu, Horvath, Tamas L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142434/
https://ncbi.nlm.nih.gov/pubmed/24074868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.09.004
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