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Rescue of defective mitogenic signaling by D-type cyclins.

Three gene products, including Myc and the D- and E-type G1 cyclins, are rate limiting for G1 progression in mammalian fibroblasts. Quiescent mouse NIH 3T3 fibroblasts engineered to express a mutant colony-stimulating factor (CSF-1) receptor (CSF-1R 809F) fail to synthesize c-myc and cyclin D1 mRNAs...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Roussel, M F, Theodoras, A M, Pagano, M, Sherr, C J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1995
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC41424/
https://ncbi.nlm.nih.gov/pubmed/7624328
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