Peroxisome proliferator-activated receptor gamma (PPARG) modulates free fatty acid receptor 1 (FFAR1) dependent insulin secretion in humans

Genetic variation in FFAR1 modulates insulin secretion dependent on non-esterified fatty acid (NEFA) concentrations. We previously demonstrated lower insulin secretion in minor allele carriers of PPARG Pro12Ala in high-NEFA environment, but the mode of action could not been revealed. We tested if th...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wagner, Robert, Hieronimus, Anja, Lamprinou, Apostolia, Heni, Martin, Hatziagelaki, Erifili, Ullrich, Susanne, Stefan, Norbert, Staiger, Harald, Häring, Hans-Ulrich, Fritsche, Andreas
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2014
Pynciau:
Brief Communication
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142395/
https://ncbi.nlm.nih.gov/pubmed/25161890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2014.07.001
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg