Diet-induced obesity elevates colonic TNF-α in mice and is accompanied by an activation of Wnt signaling: a mechanism for obesity-associated colorectal cancer()

Inflammation associated with obesity may play a role in colorectal carcinogenesis, but the underlying mechanism remains unclear. This study investigated whether the Wnt pathway, an intracellular signaling cascade that plays a critical role in colorectal carcinogenesis, is activated by obesity-induce...

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Main Authors: Liu, Zhenhua, Brooks, Ryan S., Ciappio, Eric D., Kim, Susan J., Crott, Jimmy W., Bennett, Grace, Greenberg, Andrew S., Mason, Joel B.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142203/
https://ncbi.nlm.nih.gov/pubmed/22209007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2011.07.002
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