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Structural and Functional Studies of a trans-Acyltransferase Polyketide Assembly Line Enzyme that Catalyzes Stereoselective α- and β-Ketoreduction

While the cis-acyltransferase modular polyketide synthase assembly lines have largely been structurally dissected, enzymes from within the recently discovered trans-acyltransferase polyketide synthase assembly lines are just starting to be observed crystallographically. Here we examine the ketoreduc...

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Detalhes bibliográficos
Main Authors: Piasecki, Shawn K., Zheng, Jianting, Axelrod, Abram J., Detelich, Madeline, Keatinge-Clay, Adrian T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142079/
https://ncbi.nlm.nih.gov/pubmed/24634061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24561
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