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Simplified process for the production of anti-CD19-CAR engineered T cells
BACKGROUND: Adoptive Immunotherapy using chimeric antigen receptor (CAR) engineered T cells specific for CD19 has shown promising results for the treatment of B cell lymphomas and leukemia. This therapy involves the transduction of autologous T cells with a viral vector and the subsequent cell expan...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4141724/ https://ncbi.nlm.nih.gov/pubmed/23992830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcyt.2013.06.003 |
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