Activating Signals Dominate Inhibitory Signals in CD137L/IL-15 Activated Natural Killer Cells

Natural killer (NK) cells can mediate potent antitumor effects, but factors regulating the efficiency of tumor lysis remain unclear. Studies in allogeneic stem cell transplantation highlight an important role for killer cell immunoglobulin-like receptor (KIR) mismatch in overcoming HLA-mediated inhi...

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Detalhes bibliográficos
Main Authors: Zhang, Hua, Cui, Yongzhi, Voong, Nga, Sabatino, Marianna, Stroncek, Dave F., Morisot, Sebastien, Civin, Curt I., Wayne, Alan S., Levine, Bruce L., Mackall, Crystal L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128544/
https://ncbi.nlm.nih.gov/pubmed/21304401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e31820d2a21
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