Regulation of the Interferon regulatory factor-8 (IRF-8) Tumor Suppressor Gene by the Signal Transducer and Activator of Transcription 5 (STAT5) Transcription Factor in Chronic Myeloid Leukemia

Tyrosine kinase inhibitors such as imatinib can effectively target the BCR-ABL oncoprotein in a majority of patients with chronic myeloid leukemia (CML). Unfortunately, some patients are resistant primarily to imatinib and others develop drug resistance, prompting interest in the discovery of new dr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Waight, Jeremy D., Banik, Debarati, Griffiths, Elizabeth A., Nemeth, Michael J., Abrams, Scott I.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2014
Gaiak:
Gene Regulation
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140919/
https://ncbi.nlm.nih.gov/pubmed/24753251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.544320
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