MMP3-Mediated tumor progression is controlled transcriptionally by a novel IRF8-MMP3 interaction

Interferon regulatory factor-8 (IRF8), originally identified as a leukemic tumor suppressor, can also exert anti-neoplastic activities in solid tumors. We previously showed that IRF8-loss enhanced tumor growth, which was accompanied by reduced tumor-cell susceptibility to apoptosis. However, the imp...

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Publicat a:Oncotarget
Autors principals: Banik, Debarati, Netherby, Colleen S., Bogner, Paul N., Abrams, Scott I.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558143/
https://ncbi.nlm.nih.gov/pubmed/26008967
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