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Nitration Transforms a Sensitive Peroxiredoxin 2 into a More Active and Robust Peroxidase

Peroxiredoxins (Prx) are efficient thiol-dependent peroxidases and key players in the mechanism of H(2)O(2)-induced redox signaling. Any structural change that could affect their redox state, oligomeric structure, and/or interaction with other proteins could have a significant impact on the cascade...

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Autori principali: Randall, Lía M., Manta, Bruno, Hugo, Martín, Gil, Magdalena, Batthyàny, Carlos, Trujillo, Madia, Poole, Leslie B., Denicola, Ana
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140909/
https://ncbi.nlm.nih.gov/pubmed/24719319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.539213
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