Neurolysin Knockout Mice Generation and Initial Phenotype Characterization

The oligopeptidase neurolysin (EC 3.4.24.16; Nln) was first identified in rat brain synaptic membranes and shown to ubiquitously participate in the catabolism of bioactive peptides such as neurotensin and bradykinin. Recently, it was suggested that Nln reduction could improve insulin sensitivity. He...

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Detalhes bibliográficos
Main Authors: Cavalcanti, Diogo M. L. P., Castro, Leandro M., Rosa Neto, José C., Seelaender, Marilia, Neves, Rodrigo X., Oliveira, Vitor, Forti, Fábio L., Iwai, Leo K., Gozzo, Fabio C., Todiras, Mihail, Schadock, Ines, Barros, Carlos C., Bader, Michael, Ferro, Emer S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140899/
https://ncbi.nlm.nih.gov/pubmed/24719317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.539148
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