Neurolysin Knockout Mice Generation and Initial Phenotype Characterization

The oligopeptidase neurolysin (EC 3.4.24.16; Nln) was first identified in rat brain synaptic membranes and shown to ubiquitously participate in the catabolism of bioactive peptides such as neurotensin and bradykinin. Recently, it was suggested that Nln reduction could improve insulin sensitivity. He...

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Auteurs principaux: Cavalcanti, Diogo M. L. P., Castro, Leandro M., Rosa Neto, José C., Seelaender, Marilia, Neves, Rodrigo X., Oliveira, Vitor, Forti, Fábio L., Iwai, Leo K., Gozzo, Fabio C., Todiras, Mihail, Schadock, Ines, Barros, Carlos C., Bader, Michael, Ferro, Emer S.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2014
Sujets:
Enzymology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140899/
https://ncbi.nlm.nih.gov/pubmed/24719317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.539148
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