Delineating the Importance of Serum Opsonins and the Bacterial Capsule in Affecting the Uptake and Killing of Burkholderia pseudomallei by Murine Neutrophils and Macrophages

Infection of susceptible hosts by the encapsulated Gram-negative bacterium Burkholderia pseudomallei (Bp) causes melioidosis, with septic patients attaining mortality rates ≥40%. Due to its high infectivity through inhalation and limited effective therapies, Bp is considered a potential bioweapon. T...

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Библиографические подробности
Главные авторы: Mulye, Minal, Bechill, Michael P., Grose, William, Ferreira, Viviana P., Lafontaine, Eric R., Wooten, R. Mark
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140662/
https://ncbi.nlm.nih.gov/pubmed/25144195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002988
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