Delineating the Importance of Serum Opsonins and the Bacterial Capsule in Affecting the Uptake and Killing of Burkholderia pseudomallei by Murine Neutrophils and Macrophages

Infection of susceptible hosts by the encapsulated Gram-negative bacterium Burkholderia pseudomallei (Bp) causes melioidosis, with septic patients attaining mortality rates ≥40%. Due to its high infectivity through inhalation and limited effective therapies, Bp is considered a potential bioweapon. T...

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Bibliografiska uppgifter
Huvudupphovsmän: Mulye, Minal, Bechill, Michael P., Grose, William, Ferreira, Viviana P., Lafontaine, Eric R., Wooten, R. Mark
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140662/
https://ncbi.nlm.nih.gov/pubmed/25144195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002988
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