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Enzymatic synthesis of heparin related polysaccharides on sensor chips: Rapid screening of heparin–protein interactions

The biological roles of heparin (HP) and heparan sulfate (HS) are mediated mainly through their interaction with proteins. In the present work, we provide a rapid method for screening HP/HS–protein interactions providing structural data on the key sulfo groups that participate in the binding. A libr...

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Библиографические подробности
Главные авторы: Muñoz, Eva, Xu, Ding, Avci, Fikri, Kemp, Melissa, Liu, Jian, Linhardt, Robert J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2005
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140613/
https://ncbi.nlm.nih.gov/pubmed/16310167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2005.11.051
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