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Stereoselective Synthesis of Cytotoxic Anhydrophytosphingosine Pachastrissamine (Jaspine B) from D-Xylose
[Image: see text] The first naturally occurring anhydrophytosphingosine, pachastrissamine (jaspine B), a marine compound cytotoxic toward P388, A549, HT29, and MEL28 cell lines at IC(50) = 0.01 μg/mL level, has been stereoselectively synthesized from D-xylose in 10 linear steps with 25.7% overall yi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4140561/ https://ncbi.nlm.nih.gov/pubmed/16438548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo051644y |
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