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Inhibiting Epidermal Growth Factor Receptor at a Distance
[Image: see text] The epidermal growth factor receptor (EGFR) tyrosine kinase is implicated in a large number of human cancers. Most EGFR inhibitors target the extracellular, growth factor-binding domain or the intracellular, ATP-binding domain. Here we describe molecules that inhibit the kinase act...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4140499/ https://ncbi.nlm.nih.gov/pubmed/25075632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja504076t |
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