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Probing the Phosphopantetheine Arm Conformations of Acyl Carrier Proteins Using Vibrational Spectroscopy

[Image: see text] Acyl carrier proteins (ACPs) are universal and highly conserved domains central to both fatty acid and polyketide biosynthesis. These proteins tether reactive acyl intermediates with a swinging 4′-phosphopantetheine (Ppant) arm and interact with a suite of catalytic partners during...

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Autors principals: Johnson, Matthew N. R., Londergan, Casey H., Charkoudian, Louise K.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140477/
https://ncbi.nlm.nih.gov/pubmed/25080832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja505442h
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