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Interactions of Protein Kinase C-α C1A and C1B Domains with Membranes: A Combined Computational and Experimental Study

[Image: see text] Protein kinase C-α (PKCα) has been studied widely as a paradigm for conventional PKCs, with two C1 domains (C1A and C1B) being important for the regulation and function of the kinase. However, it is challenging to explore these domains in membrane-bound environments with either sim...

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Autores principales: Li, Jianing, Ziemba, Brian P., Falke, Joseph J., Voth, Gregory A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2014
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140453/
https://ncbi.nlm.nih.gov/pubmed/25075641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja505369r
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