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C2 Domains of Protein Kinase C Isoforms α, β, and γ: Activation Parameters and Calcium Stoichiometries of the Membrane-Bound State

The independently folding C2 domain motif serves as a Ca(2+)-dependent membrane docking trigger in a large number of Ca(2+) signaling pathways. A comparison was initiated between three closely related C2 domains from the conventional protein kinase C subfamily (cPKC, isoforms α, β, and γ). The resul...

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Detalhes bibliográficos
Main Authors: Kohout, Susy C., Corbalán-García, Senena, Torrecillas, Alejandro, Goméz-Fernandéz, Juan C., Falke, Joseph J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640336/
https://ncbi.nlm.nih.gov/pubmed/12234184
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