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Identification of Ligand Analogs that Control c-di-GMP Riboswitches

Riboswitches for the bacterial second messenger c-di-GMP control the expression of genes involved in numerous cellular processes such as virulence, competence, biofilm formation and flagella synthesis. Therefore, the two known c-di-GMP riboswitch classes represent promising targets for developing no...

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Main Authors: Furukawa, Kazuhiro, Gu, Hongzhou, Sudarsan, Narasimhan, Hayakawa, Yoshihiro, Hyodo, Mamoru, Breaker, Ronald R.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140405/
https://ncbi.nlm.nih.gov/pubmed/22646696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300138n
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