Repression of Cyclin D1 Expression Is Necessary for the Maintenance of Cell Cycle Exit in Adult Mammalian Cardiomyocytes

The hearts of neonatal mice and adult zebrafish can regenerate after injury through proliferation of preexisting cardiomyocytes. However, adult mammals are not capable of cardiac regeneration because almost all cardiomyocytes exit their cell cycle. Exactly how the cell cycle exit is maintained and h...

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Detalhes bibliográficos
Main Authors: Tane, Shoji, Kubota, Misae, Okayama, Hitomi, Ikenishi, Aiko, Yoshitome, Satoshi, Iwamoto, Noriko, Satoh, Yukio, Kusakabe, Aoi, Ogawa, Satoko, Kanai, Ayumi, Molkentin, Jeffery D., Nakamura, Kazuomi, Ohbayashi, Tetsuya, Takeuchi, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140299/
https://ncbi.nlm.nih.gov/pubmed/24821722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.541953
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