Repression of Cyclin D1 Expression Is Necessary for the Maintenance of Cell Cycle Exit in Adult Mammalian Cardiomyocytes

The hearts of neonatal mice and adult zebrafish can regenerate after injury through proliferation of preexisting cardiomyocytes. However, adult mammals are not capable of cardiac regeneration because almost all cardiomyocytes exit their cell cycle. Exactly how the cell cycle exit is maintained and h...

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Dades bibliogràfiques
Autors principals: Tane, Shoji, Kubota, Misae, Okayama, Hitomi, Ikenishi, Aiko, Yoshitome, Satoshi, Iwamoto, Noriko, Satoh, Yukio, Kusakabe, Aoi, Ogawa, Satoko, Kanai, Ayumi, Molkentin, Jeffery D., Nakamura, Kazuomi, Ohbayashi, Tetsuya, Takeuchi, Takashi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140299/
https://ncbi.nlm.nih.gov/pubmed/24821722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.541953
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