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A WD Repeat Protein Controls the Cell Cycle and Differentiation by Negatively Regulating Cdc2/B-Type Cyclin Complexes

In the fission yeast Schizosaccharomyces pombe, p34(cdc2) plays a central role controlling the cell cycle. We recently isolated a new gene named srw1(+), capable of encoding a WD repeat protein, as a multicopy suppressor of hyperactivated p34(cdc2). Cells lacking srw1(+) are sterile and defective in...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Satoko, Murakami, Hiroshi, Okayama, Hiroto
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 1997
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC25721/
https://ncbi.nlm.nih.gov/pubmed/9398669
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