Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2.
The human anti-oncoprotein p53 is shown to be a substrate of cdc2. The primary site of phosphorylation is serine-315. Serine-315 is phosphorylated by both p60-cdc2 and cyclin B-cdc2 enzymes. The phosphorylation of p53 is cell cycle-dependent. The abundance of p53 also oscillates during the cell cycl...
Gespeichert in:
| Veröffentlicht in: | Proc Natl Acad Sci U S A |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1990
|
| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54198/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2141171/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.12.4766 |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|