Interactions of the Protein-tyrosine Phosphatase-α with the Focal Adhesion Targeting Domain of Focal Adhesion Kinase Are Involved in Interleukin-1 Signaling in Fibroblasts

Interleukin-1 (IL-1) signaling in fibroblasts is mediated through focal adhesions, organelles that are enriched with adaptor and cytoskeletal proteins that regulate signal transduction. We examined interactions of the focal adhesion kinase (FAK) with protein-tyrosine phosphatase-α (PTP-α) in IL-1 si...

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Autores principales: Wang, Qin, Wang, Yongqiang, Fritz, Dominik, Rajshankar, Dhaarmini, Downey, Gregory P., McCulloch, Christopher A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140282/
https://ncbi.nlm.nih.gov/pubmed/24821720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.540294
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