Importance of Protein-tyrosine Phosphatase-α Catalytic Domains for Interactions with SHP-2 and Interleukin-1-induced Matrix Metalloproteinase-3 Expression

Interleukin-1 (IL-1) induces extracellular matrix degradation as a result of increased expression of matrix metalloproteinases (MMPs). We examined adhesion-restricted signaling pathways that enable IL-1-induced MMP release in human gingival and murine fibroblasts. Of the seven MMPs and three tissue...

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Detalhes bibliográficos
Main Authors: Wang, Qin, Rajshankar, Dhaarmini, Laschinger, Carol, Talior-Volodarsky, Ilana, Wang, Yongqiang, Downey, Gregory P., McCulloch, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903391/
https://ncbi.nlm.nih.gov/pubmed/20472558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.102426
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