Collaborator of ARF (CARF) Regulates Proliferative Fate of Human Cells by Dose-dependent Regulation of DNA Damage Signaling

Collaborator of ARF (CARF) has been shown to directly bind to and regulate p53, a central protein that controls tumor suppression via cellular senescence and apoptosis. However, the cellular functions of CARF and the mechanisms governing its effect on senescence, apoptosis, or proliferation are stil...

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Detalhes bibliográficos
Main Authors: Cheung, Caroline T., Singh, Rumani, Kalra, Rajkumar S., Kaul, Sunil C., Wadhwa, Renu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140265/
https://ncbi.nlm.nih.gov/pubmed/24825908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.547208
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