Tumor suppressor activity of miR-451: Identification of CARF as a new target

microRNAs (miRs) have recently emerged as small non-coding regulators of gene expression. We performed a loss-of-function screening by recruiting retrovirus mediated arbitrary manipulation of genome coupled with escape of cells from 5-Aza-2′-deoxycytidine (5-Aza-dC)-induced senescence. miRNA pool fr...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Li, Ling, Gao, Ran, Yu, Yue, Kaul, Zeenia, Wang, Jia, Kalra, Rajkumar S., Zhang, Zhenya, Kaul, Sunil C., Wadhwa, Renu
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762681/
https://ncbi.nlm.nih.gov/pubmed/29321561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18559-5
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