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CARF (Collaborator of ARF) overexpression in p53‐deficient cells promotes carcinogenesis
Collaborator of ARF (CARF), initially identified as a binding partner of ARF (Alternate Reading Frame), has been shown to activate ARF–p53 pathway by multiple ways including stabilization of ARF and p53 tumor suppressor proteins, and transcriptional repression of a p53 antagonist, HDM2. Level of CAR...
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Publicado no: | Mol Oncol |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
John Wiley and Sons Inc.
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5528716/ https://ncbi.nlm.nih.gov/pubmed/26278998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.07.003 |
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