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CARF (Collaborator of ARF) overexpression in p53‐deficient cells promotes carcinogenesis

Collaborator of ARF (CARF), initially identified as a binding partner of ARF (Alternate Reading Frame), has been shown to activate ARF–p53 pathway by multiple ways including stabilization of ARF and p53 tumor suppressor proteins, and transcriptional repression of a p53 antagonist, HDM2. Level of CAR...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Oncol
Hauptverfasser: Kalra, Rajkumar S., Cheung, Caroline T., Chaudhary, Anupama, Prakash, Jay, Kaul, Sunil C., Wadhwa, Renu
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528716/
https://ncbi.nlm.nih.gov/pubmed/26278998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.07.003
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