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Increased O-GlcNAc Levels Correlate with Decreased O-GlcNAcase Levels in Alzheimer Disease Brain

The potential role of the posttranslational modification of proteins with O-linked N-acetyl-β-D-glucosamine (O-GlcNAc) in the pathogenesis of Alzheimer disease (AD) has been studied extensively, yet the exact function of O-GlcNAc in AD remains elusive. O-GlcNAc cycling is facilitated by only two hig...

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Main Authors: Förster, Sarah, Welleford, Andrew S., Triplett, Judy C., Sultana, Rukhsana, Schmitz, Brigitte, Butterfield, D. Allan
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140188/
https://ncbi.nlm.nih.gov/pubmed/24859566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2014.05.014
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